VoodooShield

VoodooShield is a security program that is unlike most traditional anti-virus programs. Instead of scanning your computer for known malware or using definition files to detect infections, VoodooShield instead locks your computer so that you are notified when an unknown process is started.  This allows you to lock down your computer so that it only executes applications that you specifically whitelist and denies all other programs.  This makes it impossible for an application to run without you first giving your express approval.