Hello,
I've also been trying to get Theme Hospital to work on my Dell Inspiron 4000 running Windows ME. I've tried an .iso file where none of the .exe files work (not a valid Win-32 executable). I have another install of the game I got from the gog.com release of the game. That one keeps giving me a "CD-ROM needed to play" error. I can't find another .iso file to try to get it to work. Can anyone help me out here?